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Repeated Exposure of Escherichia coli to High Ciprofloxacin Concentrations Selects gyrB Mutants That Show Fluoroquinolone-Specific Hyperpersistence

Recent studies have shown that not only resistance, but also tolerance/persistence levels can evolve rapidly in bacteria exposed to repeated antibiotic treatments. We used in vitro evolution to assess whether tolerant/hyperpersistent Escherichia coli ATCC25922 mutants could be selected under repeate...

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Detalles Bibliográficos
Autores principales: Perault, Aurore, Turlan, Catherine, Eynard, Nathalie, Vallé, Quentin, Bousquet-Mélou, Alain, Giraud, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189390/
https://www.ncbi.nlm.nih.gov/pubmed/35707170
http://dx.doi.org/10.3389/fmicb.2022.908296