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Ursolic acid inhibits Th17 cell differentiation via STAT3/RORγt pathway and suppresses Schwann cell-mediated Th17 cell migration by reducing CXCL9/10 expression

Th17 cells represent important immune cells. Ursolic acid (UA) can regulate immune cell activities. This study was aimed to explore the effects of UA on Th17 cell differentiation and Schwann cell(SCs)-mediated migration and the potential mechanism. Naïve CD4(+) T cells were isolated from rat periphe...

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Detalles Bibliográficos
Autores principales: Xu, Hua, Yu, Ai-ling, Zhao, Da-peng, Meng, Guang-yuan, Wang, Ling, Shan, Min, Hu, Nai-xia, Liu, Yun-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189552/
https://www.ncbi.nlm.nih.gov/pubmed/35548957
http://dx.doi.org/10.1177/17534259221094559