Cargando…
Ursolic acid inhibits Th17 cell differentiation via STAT3/RORγt pathway and suppresses Schwann cell-mediated Th17 cell migration by reducing CXCL9/10 expression
Th17 cells represent important immune cells. Ursolic acid (UA) can regulate immune cell activities. This study was aimed to explore the effects of UA on Th17 cell differentiation and Schwann cell(SCs)-mediated migration and the potential mechanism. Naïve CD4(+) T cells were isolated from rat periphe...
Autores principales: | Xu, Hua, Yu, Ai-ling, Zhao, Da-peng, Meng, Guang-yuan, Wang, Ling, Shan, Min, Hu, Nai-xia, Liu, Yun-lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189552/ https://www.ncbi.nlm.nih.gov/pubmed/35548957 http://dx.doi.org/10.1177/17534259221094559 |
Ejemplares similares
-
RORγt and RORα signature genes in human Th17 cells
por: Castro, Glenda, et al.
Publicado: (2017) -
lncRNA STAT4-AS1 Inhibited TH17 Cell Differentiation by Targeting RORγt Protein
por: He, Hanlin, et al.
Publicado: (2022) -
Transcription of RORγt in Developing Th17 Cells is Regulated by E-Proteins
por: Zhang, Fuping, et al.
Publicado: (2013) -
SIRT1 deacetylates RORγt and enhances Th17 cell generation
por: Lim, Hyung W., et al.
Publicado: (2015) -
SIRT1 deacetylates RORγt and enhances Th17 cell generation
por: Lim, Hyung W., et al.
Publicado: (2015)