Cargando…

Reduced Bone Mass in Collagen Prolyl 4‐Hydroxylase P4ha1 (+/−); P4ha2 (−/−) Compound Mutant Mice

Proper deposition of the extracellular matrix and its major components, the collagens, is essential for endochondral ossification and bone mass accrual. Collagen prolyl 4‐hydroxylases (C‐P4Hs) hydroxylate proline residues in the ‐X‐Pro‐Gly‐ repeats of all known collagen types. Their product, 4‐hydro...

Descripción completa

Detalles Bibliográficos
Autores principales: Tolonen, Jussi‐Pekka, Salo, Antti M, Finnilä, Mikko, Aro, Ellinoora, Karjalainen, Emma, Ronkainen, Veli‐Pekka, Drushinin, Kati, Merceron, Christophe, Izzi, Valerio, Schipani, Ernestina, Myllyharju, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189910/
https://www.ncbi.nlm.nih.gov/pubmed/35720665
http://dx.doi.org/10.1002/jbm4.10630