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Reduced Bone Mass in Collagen Prolyl 4‐Hydroxylase P4ha1 (+/−); P4ha2 (−/−) Compound Mutant Mice
Proper deposition of the extracellular matrix and its major components, the collagens, is essential for endochondral ossification and bone mass accrual. Collagen prolyl 4‐hydroxylases (C‐P4Hs) hydroxylate proline residues in the ‐X‐Pro‐Gly‐ repeats of all known collagen types. Their product, 4‐hydro...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189910/ https://www.ncbi.nlm.nih.gov/pubmed/35720665 http://dx.doi.org/10.1002/jbm4.10630 |