LTBK-03. Targeted mass spectrometry of serial CSF and serum specimens from children with diffuse intrinsic pontine glioma treated with intracranial B7-H3 CAR T cells

Considering the high expression of B7-H3 (CD276) on diffuse intrinsic pontine glioma (DIPG) and preliminary evidence that repeated locoregional delivery of CAR T cells to patients with CNS tumors was feasible and tolerable, we open the phase 1 trial BrainChild-03 (NCT04185038). Children with DIPG in...

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Detalles Bibliográficos
Autores principales: Vitanza, Nicholas, Wilson, Ashley, Huang, Wenjun, Whiteaker, Jeffrey, Gust, Juliane, Orentas, Rimas, Gardner, Rebecca, Park, Julie, Jensen, Michael, Paulovich, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Late Breaking Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189940/
http://dx.doi.org/10.1093/neuonc/noac079.715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189940/
http://dx.doi.org/10.1093/neuonc/noac079.715

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