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SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity

Serum- and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that plays important roles in the cellular stress response. While SGK1 has been reported to restrain inflammatory immune responses, the molecular mechanisms involved remain elusive, especially in oral bacteria-induced i...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Ren, Junling, Lohner, Hannah, Yakoumatos, Lan, Liang, Ruqiang, Wang, Huizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190018/
https://www.ncbi.nlm.nih.gov/pubmed/35588785
http://dx.doi.org/10.1016/j.jbc.2022.102036