A novel Cbx1, PurB, and Sp3 complex mediates long-term silencing of tissue- and lineage-specific genes

miRNA-based cellular fate reprogramming offers an opportunity to investigate the mechanisms of long-term gene silencing. To further understand how genes are silenced in a tissue-specific manner, we leveraged our miRNA-based method of reprogramming fibroblasts into cardiomyocytes. Through screening a...

Descripción completa

Detalles Bibliográficos
Autores principales: Baksh, Syeda Samara, Pratt, Richard E., Gomez, José, Dzau, Victor J., Hodgkinson, Conrad P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190063/
https://www.ncbi.nlm.nih.gov/pubmed/35605661
http://dx.doi.org/10.1016/j.jbc.2022.102053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190063/
https://www.ncbi.nlm.nih.gov/pubmed/35605661
http://dx.doi.org/10.1016/j.jbc.2022.102053

Ejemplares similares