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Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants

BACKGROUND: Despite early interest in the health effects of polyunsaturated fatty acids (PUFA), there is still substantial controversy and uncertainty on the evidence linking PUFA to cardiovascular diseases (CVDs). We investigated the effect of plasma concentration of omega-3 PUFA (i.e. docosahexaen...

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Detalles Bibliográficos
Autores principales: Borges, Maria Carolina, Haycock, Philip C., Zheng, Jie, Hemani, Gibran, Holmes, Michael V., Davey Smith, George, Hingorani, Aroon D., Lawlor, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190170/
https://www.ncbi.nlm.nih.gov/pubmed/35692035
http://dx.doi.org/10.1186/s12916-022-02399-w