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UNC13B Promote Arsenic Trioxide Resistance in Chronic Lymphoid Leukemia Through Mitochondria Quality Control

In clinical practice, arsenic trioxide can be used to treat a subset of R/R CML patients, but resistance tends to reappear quickly. We designed an experiment to study arsenic trioxide resistance in K-562 cells. Previously, we identified the UNC13B gene as potentially responsible for arsenic trioxide...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Bo, Yuan, Li-Hua, Yan, Le-Ping, Ye, Yong-Bin, Lu, Bo, Xu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190243/
https://www.ncbi.nlm.nih.gov/pubmed/35707364
http://dx.doi.org/10.3389/fonc.2022.920999