A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila

CRISPR-based gene-drives have been proposed for managing insect populations, including disease-transmitting mosquitoes, due to their ability to bias their inheritance toward super-Mendelian rates (>50%). Current technologies use a Cas9 that introduces DNA double-strand breaks into the opposing wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Amo, Víctor López Del, Juste, Sara Sanz, Gantz, Valentino M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190248/
https://www.ncbi.nlm.nih.gov/pubmed/35613590
http://dx.doi.org/10.1016/j.celrep.2022.110843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190248/
https://www.ncbi.nlm.nih.gov/pubmed/35613590
http://dx.doi.org/10.1016/j.celrep.2022.110843

Ejemplares similares