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A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila
CRISPR-based gene-drives have been proposed for managing insect populations, including disease-transmitting mosquitoes, due to their ability to bias their inheritance toward super-Mendelian rates (>50%). Current technologies use a Cas9 that introduces DNA double-strand breaks into the opposing wi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190248/ https://www.ncbi.nlm.nih.gov/pubmed/35613590 http://dx.doi.org/10.1016/j.celrep.2022.110843 |