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LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation

Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4/GPR48), a member of the GPCR (G protein-coupled receptors) superfamily, subfamily B, is a common intestinal crypt stem cell marker. It binds R-spondins/Norrin as classical ligands and plays a crucial role in Wnt signaling potentiation...

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Detalles Bibliográficos
Autores principales: Filipowska, Joanna, Kondegowda, Nagesha G., Leon-Rivera, Nancy, Dhawan, Sangeeta, Vasavada, Rupangi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190282/
https://www.ncbi.nlm.nih.gov/pubmed/35707461
http://dx.doi.org/10.3389/fendo.2022.867001