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LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation
Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4/GPR48), a member of the GPCR (G protein-coupled receptors) superfamily, subfamily B, is a common intestinal crypt stem cell marker. It binds R-spondins/Norrin as classical ligands and plays a crucial role in Wnt signaling potentiation...
Autores principales: | Filipowska, Joanna, Kondegowda, Nagesha G., Leon-Rivera, Nancy, Dhawan, Sangeeta, Vasavada, Rupangi C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190282/ https://www.ncbi.nlm.nih.gov/pubmed/35707461 http://dx.doi.org/10.3389/fendo.2022.867001 |
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