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Nuclear βII-Tubulin and its Possible Utility in Cancer Diagnosis, Prognosis and Treatment

Microtubules are organelles that usually occur only in the cytosol. Walss et al. (1999) discovered the βII isotype of tubulin, complexed with α, in the nuclei of certain cultured cells, in non-microtubule form. When fluorescently labeled tubulins were microinjected into the cells, only αβII appeared...

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Detalles Bibliográficos
Autores principales: Ludueña, Richard F., Walss-Bass, Consuelo, Portyanko, Anna, Guo, Jiayan, Yeh, I-Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190298/
https://www.ncbi.nlm.nih.gov/pubmed/35706904
http://dx.doi.org/10.3389/fcell.2022.870088