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A Novel Adult Murine Model of Typical Enteroaggregative Escherichia coli Infection Reveals Microbiota Dysbiosis, Mucus Secretion, and AAF/II-Mediated Expression and Localization of β-Catenin and Expression of MUC1 in Ileum

Typical enteroaggregative Escherichia coli (tEAEC) is a diarrheagenic E. coli pathotype associated with pediatric and traveler’s diarrhea. Even without diarrhea, EAEC infections in children also lead to increased gut inflammation and growth shortfalls. EAEC strain’s defining phenotype is the aggrega...

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Detalles Bibliográficos
Autores principales: Moran-Garcia, Nadia, Lopez-Saucedo, Catalina, Becerra, Adriana, Meza-Segura, Mario, Hernandez-Cazares, Felipe, Guerrero-Baez, Jair, Galindo-Gómez, Silvia, Tsutsumi, Víctor, Schnoor, Michael, Méndez-Tenorio, Alfonso, Nataro, James P., Estrada-Garcia, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190437/
https://www.ncbi.nlm.nih.gov/pubmed/35706909
http://dx.doi.org/10.3389/fcimb.2022.885191