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In vivo Mammalian Alkaline Comet Assay: Method Adapted for Genotoxicity Assessment of Nanomaterials

The in vivo Comet assay measures the generation of DNA strand breaks under conditions in which the DNA will unwind and migrate to the anode in an electrophoresis assay, producing comet-like figures. Measurements are on single cells, which allows the sampling of a diversity of cells and tissues for D...

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Detalles Bibliográficos
Autores principales: Cardoso, Renato, Dusinska, Maria, Collins, Andrew, Manjanatha, Mugimane, Pfuhler, Stefan, Registre, Marilyn, Elespuru, Rosalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191202/
https://www.ncbi.nlm.nih.gov/pubmed/35707495
http://dx.doi.org/10.3389/ftox.2022.903896