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Targeting EGFR Tyrosine Kinase: Design, Synthesis and Biological Evaluation of Novel Quinazolinone Derivatives

Impaired cell cycle regulation and disturbance in signal transduction pathway are two major causes of a condition defined as cancer, one of the significant reasons for mortality worldwide. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been commonly used as anticancer a...

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Detalles Bibliográficos
Autores principales: Nematpour, Manijeh, Rezaee, Elham, Nazari, Maryam, Hosseini, Omid, Tabatabai, Sayyed Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Briefland 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191221/
https://www.ncbi.nlm.nih.gov/pubmed/35765503
http://dx.doi.org/10.5812/ijpr.123826