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Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative
The human voltage-gated proton channel (hHv1) is important for control of intracellular pH. We designed C6, a specific peptide inhibitor of hHv1, to evaluate the roles of the channel in sperm capacitation and in the inflammatory immune response of neutrophils [R. Zhao et al., Proc. Natl. Acad. Sci....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191634/ https://www.ncbi.nlm.nih.gov/pubmed/35648818 http://dx.doi.org/10.1073/pnas.2120750119 |