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The nonclassical MHC class I Qa-1 expressed in layer 6 neurons regulates activity-dependent plasticity via microglial CD94/NKG2 in the cortex

During developmental critical periods, circuits are sculpted by a process of activity-dependent competition. The molecular machinery involved in regulating the complex process of responding to different levels of activity is now beginning to be identified. Here, we show that the nonclassical major h...

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Detalles Bibliográficos
Autores principales: Marin, Ioana A., Gutman-Wei, Alan Y., Chew, Kylie S., Raissi, Aram J., Djurisic, Maja, Shatz, Carla J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191652/
https://www.ncbi.nlm.nih.gov/pubmed/35648829
http://dx.doi.org/10.1073/pnas.2203965119