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The nonclassical MHC class I Qa-1 expressed in layer 6 neurons regulates activity-dependent plasticity via microglial CD94/NKG2 in the cortex
During developmental critical periods, circuits are sculpted by a process of activity-dependent competition. The molecular machinery involved in regulating the complex process of responding to different levels of activity is now beginning to be identified. Here, we show that the nonclassical major h...
Autores principales: | Marin, Ioana A., Gutman-Wei, Alan Y., Chew, Kylie S., Raissi, Aram J., Djurisic, Maja, Shatz, Carla J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191652/ https://www.ncbi.nlm.nih.gov/pubmed/35648829 http://dx.doi.org/10.1073/pnas.2203965119 |
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