Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA

Pneumococcal conjugate vaccines (PCVs) used in childhood vaccination programs have resulted in replacement of vaccine-type with nonvaccine-type pneumococci in carriage and invasive pneumococcal disease (IPD). A vaccine based on highly conserved and protective pneumococcal antigens is urgently needed...

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Detalles Bibliográficos
Autores principales: Narciso, Ana Rita, Iovino, Federico, Thorsdottir, Sigrun, Mellroth, Peter, Codemo, Mario, Spoerry, Christian, Righetti, Francesco, Muschiol, Sandra, Normark, Staffan, Nannapaneni, Priyanka, Henriques-Normark, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191655/
https://www.ncbi.nlm.nih.gov/pubmed/35648835
http://dx.doi.org/10.1073/pnas.2122386119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191655/
https://www.ncbi.nlm.nih.gov/pubmed/35648835
http://dx.doi.org/10.1073/pnas.2122386119

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