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Suppression of choroidal neovascularization and epithelial-mesenchymal transition in retinal pigmented epithelium by adeno-associated virus-mediated overexpression of CCN5 in mice

Choroidal neovascularization (CNV) is a defining characteristic feature of neovascular age-related macular degeneration (nAMD) that frequently results in irreversible vision loss. The current strategies for the treatment of nAMD are mainly based on neutralizing vascular endothelial growth factor (VE...

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Detalles Bibliográficos
Autores principales: Im, Sora, Han, Jung Woo, Park, Euy Jun, Bang, Ji Hong, Shin, Hee Jeong, Chang, Hun Soo, Woo, Kee Min, Park, Woo Jin, Park, Tae Kwann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191714/
https://www.ncbi.nlm.nih.gov/pubmed/35696413
http://dx.doi.org/10.1371/journal.pone.0269937