Cytosolic aspartate aminotransferase moonlights as a ribosome-binding modulator of Gcn2 activity during oxidative stress

Regulation of translation is a fundamental facet of the cellular response to rapidly changing external conditions. Specific RNA-binding proteins (RBPs) co-ordinate the translational regulation of distinct mRNA cohorts during stress. To identify RBPs with previously under-appreciated roles in transla...

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Detalles Bibliográficos
Autores principales: Crawford, Robert A, Ashe, Mark P, Hubbard, Simon J, Pavitt, Graham D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191892/
https://www.ncbi.nlm.nih.gov/pubmed/35621265
http://dx.doi.org/10.7554/eLife.73466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191892/
https://www.ncbi.nlm.nih.gov/pubmed/35621265
http://dx.doi.org/10.7554/eLife.73466

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