Glucose metabolism inhibitor PFK-015 combined with immune checkpoint inhibitor is an effective treatment regimen in cancer

Metabolic inhibition via PFKFB3 inhibition has demonstrated considerable tumor inhibitory effects in various studies; however, PFKFB3 inhibition did not show satisfactory tumor inhibition when used in clinical trials. PFKFB3 is a crucial metabolic enzyme that is highly upregulated in cancer cells an...

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Detalles Bibliográficos
Autores principales: Zheng, Jia Bo, Wong, Chau Wei, Liu, Jia, Luo, Xiao-Jing, Zhou, Wei-Yi, Chen, Yan-Xing, Luo, Hui-Yan, Zeng, Zhao-Lei, Ren, Chao, Xie, Xiao-Ming, Wang, De-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191911/
https://www.ncbi.nlm.nih.gov/pubmed/35707221
http://dx.doi.org/10.1080/2162402X.2022.2079182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9191911/
https://www.ncbi.nlm.nih.gov/pubmed/35707221
http://dx.doi.org/10.1080/2162402X.2022.2079182

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