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Silencing the ADAM9 Gene through CRISPR/Cas9 Protects Mice from Alcohol-Induced Acute Liver Injury

Alcoholic liver injury is a major global public health concern at present. The ADAM9 gene plays a crucial role in the occurrence and development of various liver diseases, but its role in acute alcoholic liver injury remains ambiguous. In this study, a chimeric single-guide RNA targeting the genomic...

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Detalles Bibliográficos
Autores principales: Zhang, Yong-Yong, Li, San-Qiang, Song, Ying, Wang, Ping, Song, Xiao-Gai, Zhu, Wen-Feng, Wang, Dong-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192226/
https://www.ncbi.nlm.nih.gov/pubmed/35707386
http://dx.doi.org/10.1155/2022/5110161