High-Risk Polymorphisms Associated with the Molecular Function of Human HMGCR Gene Infer the Inhibition of Cholesterol Biosynthesis

HMG-CoA reductase or HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase) is a rate-limiting enzyme involved in cholesterol biosynthesis. HMGCR plays an important role in the possible occurrence of hypercholesterolemia leading to atherosclerosis and coronary heart disease. This enzyme is a major target...

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Detalles Bibliográficos
Autores principales: Das, Keshob Chandra, Hossain, Mohammad Uzzal, Moniruzzaman, Md, Salimullah, Md, Akhteruzzaman, Sharif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192228/
https://www.ncbi.nlm.nih.gov/pubmed/35707384
http://dx.doi.org/10.1155/2022/4558867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192228/
https://www.ncbi.nlm.nih.gov/pubmed/35707384
http://dx.doi.org/10.1155/2022/4558867

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