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Paradigm shift: new concepts for HCN4 function in cardiac pacemaking

Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels are the molecular correlate of the I(f) current and are critically involved in controlling neuronal excitability and the autonomous rhythm of the heart. The HCN4 isoform is the main HCN channel subtype expressed in the sinoatrial nod...

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Detalles Bibliográficos
Autores principales: Hennis, Konstantin, Biel, Martin, Fenske, Stefanie, Wahl-Schott, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192375/
https://www.ncbi.nlm.nih.gov/pubmed/35556164
http://dx.doi.org/10.1007/s00424-022-02698-4