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Histone H3K36me2 demethylase KDM2A promotes bladder cancer progression through epigenetically silencing RARRES3

Epigenetic dysregulation contributes to bladder cancer tumorigenesis. H3K36me2 demethylase KDM2A functions as an important epigenetic regulator of cell fate in many types of tumors. However, its role in bladder cancer remains unknown. Here, we revealed a positive correlation between KDM2A gene copy...

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Detalles Bibliográficos
Autores principales: Lu, Bing, Wei, Jiatian, Zhou, Houhong, Chen, Jie, Li, Yuqing, Ye, Liefu, Zhao, Wei, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192503/
https://www.ncbi.nlm.nih.gov/pubmed/35697678
http://dx.doi.org/10.1038/s41419-022-04983-7