Luseogliflozin preserves the pancreatic beta-cell mass and function in db/db mice by improving mitochondrial function

We aimed to determine the mechanism by which the sodium glucose co-transporter 2 inhibitor, luseogliflozin, preserves pancreatic beta-cell mass and function in db/db mice. Six-week-old db/db mice were fed to standard chow or standard chow containing 0.01% luseogliflozin. After 4 weeks, DNA microarra...

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Detalles Bibliográficos
Autores principales: Yamauchi, Yuki, Nakamura, Akinobu, Yokota, Takashi, Takahashi, Kiyohiko, Kawata, Shinichiro, Tsuchida, Kazuhisa, Omori, Kazuno, Nomoto, Hiroshi, Kameda, Hiraku, Cho, Kyu Yong, Anzai, Toshihisa, Tanaka, Shinya, Terauchi, Yasuo, Miyoshi, Hideaki, Atsumi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192642/
https://www.ncbi.nlm.nih.gov/pubmed/35697838
http://dx.doi.org/10.1038/s41598-022-13888-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192642/
https://www.ncbi.nlm.nih.gov/pubmed/35697838
http://dx.doi.org/10.1038/s41598-022-13888-6

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