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Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine

Labile redox-active iron ions have been implicated in various neurodegenerative disorders, including the Parkinson's disease (PD). Iron chelation has been successfully used in clinical practice to manage iron overload in diseases such as thalassemia major; however, the use of conventional iron...

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Detalles Bibliográficos
Autores principales: Hašková, Pavlína, Applová, Lenka, Jansová, Hana, Homola, Pavel, Franz, Katherine J., Vávrová, Kateřina, Roh, Jaroslav, Šimůnek, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192712/
https://www.ncbi.nlm.nih.gov/pubmed/35697900
http://dx.doi.org/10.1038/s41598-022-13554-x