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Ribosome profiling reveals multiple roles of SecA in cotranslational protein export

SecA, an ATPase known to posttranslationally translocate secretory proteins across the bacterial plasma membrane, also binds ribosomes, but the role of SecA’s ribosome interaction has been unclear. Here, we used a combination of ribosome profiling methods to investigate the cotranslational actions o...

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Detalles Bibliográficos
Autores principales: Zhu, Zikun, Wang, Shuai, Shan, Shu-ou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192764/
https://www.ncbi.nlm.nih.gov/pubmed/35697696
http://dx.doi.org/10.1038/s41467-022-31061-5