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PET imaging of an optimized anti-PD-L1 probe (68)Ga-NODAGA-BMS986192 in immunocompetent mice and non-human primates

BACKGROUND: Adnectin is a protein family derived from the 10th type III domain of human fibronectin ((10)Fn3) with high-affinity targeting capabilities. Positron emission tomography (PET) probes derived from anti-programmed death ligand-1 (PD-L1) Adnectins, including (18)F- and (68)Ga-labeled BMS-98...

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Detalles Bibliográficos
Autores principales: Zhou, Huimin, Bao, Guangfa, Wang, Ziqiang, Zhang, Buchuan, Li, Dan, Chen, Lixing, Deng, Xiaoyun, Yu, Bo, Zhao, Jun, Zhu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9192916/
https://www.ncbi.nlm.nih.gov/pubmed/35695985
http://dx.doi.org/10.1186/s13550-022-00906-x