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The Influence of EGCG on the Pharmacokinetics and Pharmacodynamics of Bisoprolol and a New Method for Simultaneous Determination of EGCG and Bisoprolol in Rat Plasma

BACKGROUND AND AIM: Research has shown that green tea catechins may influence the activity of drug metabolizing enzymes and drug transporters. We examined whether epigallocatechin-3-gallate (EGCG) affected the pharmacokinetics and pharmacodynamics of bisoprolol in rats. METHODS: A sensitive, specifi...

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Detalles Bibliográficos
Autores principales: Zeng, Weiwei, Lao, Sixian, Guo, Yi, Wu, Yufeng, Huang, Min, Tomlinson, Brian, Zhong, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193186/
https://www.ncbi.nlm.nih.gov/pubmed/35711541
http://dx.doi.org/10.3389/fnut.2022.907986