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The Influence of EGCG on the Pharmacokinetics and Pharmacodynamics of Bisoprolol and a New Method for Simultaneous Determination of EGCG and Bisoprolol in Rat Plasma
BACKGROUND AND AIM: Research has shown that green tea catechins may influence the activity of drug metabolizing enzymes and drug transporters. We examined whether epigallocatechin-3-gallate (EGCG) affected the pharmacokinetics and pharmacodynamics of bisoprolol in rats. METHODS: A sensitive, specifi...
Autores principales: | Zeng, Weiwei, Lao, Sixian, Guo, Yi, Wu, Yufeng, Huang, Min, Tomlinson, Brian, Zhong, Guoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193186/ https://www.ncbi.nlm.nih.gov/pubmed/35711541 http://dx.doi.org/10.3389/fnut.2022.907986 |
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