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Diet-Induced Mouse Model of Nonalcoholic Steatohepatitis That Replicates the Human Disease
OBJECTIVES: Developing a mouse model of nonalcoholic steatohepatitis (NASH) with obesity and fibrosis. METHODS: We fed agouti yellow male mice, which are hyperphagic, a western diet and water containing high fructose corn syrup for either 16 weeks or a year. We measured body weight and composition;...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193353/ http://dx.doi.org/10.1093/cdn/nzac058.002 |