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Diet-Induced Mouse Model of Nonalcoholic Steatohepatitis That Replicates the Human Disease

OBJECTIVES: Developing a mouse model of nonalcoholic steatohepatitis (NASH) with obesity and fibrosis. METHODS: We fed agouti yellow male mice, which are hyperphagic, a western diet and water containing high fructose corn syrup for either 16 weeks or a year. We measured body weight and composition;...

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Detalles Bibliográficos
Autores principales: Caviglia, Jorge, St Rose, Kristy, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193353/
http://dx.doi.org/10.1093/cdn/nzac058.002