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Epicatechin Mitigates Anxiety-Related Behavior in a Mouse Model of Obesity by Modulating Gut Microbiome Composition and Global Gene Expression Profile in the Hippocampus

OBJECTIVES: Epicatechin (EC) is a flavan-3-ol abundant in cocoa, apples, and tea, and can prevent vascular dysfunction and development of diseases, such as cardiovascular or neurodegenerative diseases. We have recently shown that EC can prevent lipid-induced brain endothelial cell dysfunction by mod...

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Detalles Bibliográficos
Autores principales: Milenkovic, Dragan, Kang, Jiye, Wang, Ziwei, Cremonini, Eleonora, Vauzour, David, Oteiza, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193357/
http://dx.doi.org/10.1093/cdn/nzac053.057