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Flavonoids Ameliorate Stress-Induced Depression by Preventing NLRP3 Inflammasome Priming
OBJECTIVES: Chronic stress activates danger-associated molecular patterns (DAMPs), stimulating the NLRP3 inflammasome. NLRP3 activation triggers the release of pro-inflammatory cytokine IL‐1β. The activity of the NLRP3 inflammasome propagates pro-inflammatory signaling cascades implicated in the ons...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193675/ http://dx.doi.org/10.1093/cdn/nzac064.021 |