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Paracrine Signaling From Pancreatic Ductal Cancer Cells Induced Programmed-Cell Death in 3T3-L1 Adipocytes Through Apoptosis and Ferroptosis

OBJECTIVES: Cancer cachexia is a prominent feature of patients with pancreatic ductal adenocarcinoma (PDAC). Cachexia is characterized by aberrant inflammatory responses, rapid loss of fat and muscle mass. Emerging evidence revealed that adipose tissue loss precedes muscle loss in those with cancer...

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Detalles Bibliográficos
Autores principales: Khoo, Vivien, Kim, Young-Cheul, Hollingsworth, Micheal, Kim, So-youn, Chung, Soonkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193735/
http://dx.doi.org/10.1093/cdn/nzac052.011