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Acute Exposure to Branched-Chain Amino Acids (BCAAs) Impairs Glucose Homeostasis by Promoting Insulin Resistance in Mice

OBJECTIVES: Increased plasma BCAAs are associated with T2D. Current evidence suggests that high BCAAs are detrimental to insulin action and glucose metabolism. Chronic supplementation of BCAAs results in development of insulin resistance whereas dietary restriction of BCAAs improves insulin sensitiv...

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Detalles Bibliográficos
Autores principales: Gannaban, Ritchel, Shah, Harsh, Shin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9193819/
http://dx.doi.org/10.1093/cdn/nzac047.020