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Sex Disparity in Alcohol-Induced Inflammation and Oxidative Stress in Macrophage-Specific Histone Deacetylase 4 Knockout Mice

OBJECTIVES: We have previously shown that histone deacetylase 4 (HDAC4), a class IIa histone deacetylase expression was increased in alcohol-induced inflammation of macrophages in vitro. We determined the role of macrophage HDAC4 in the pathogenesis of alcoholic hepatitis (AH). METHODS: Human liver...

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Detalles Bibliográficos
Autores principales: Kang, Hyunju, Kim, Mi-bo, Jang, Hyungryun, Corvino, Olivia, Park, Young-ki, Lee, Ji-young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194174/
http://dx.doi.org/10.1093/cdn/nzac068.013