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The paradox of radiation and T cells in tumors

In this review we consider what appears to be a paradox in immunotherapies based around radiation therapy. The paradox is based on three main points. 1. That T cells are needed for radiation's efficacy; 2. That tumor-specific T cells are enriched in the field of treatment; and 3. That radiation...

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Detalles Bibliográficos
Autores principales: Gough, Michael J., Crittenden, Marka R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194456/
https://www.ncbi.nlm.nih.gov/pubmed/35691060
http://dx.doi.org/10.1016/j.neo.2022.100808