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New synthesis of a late-stage tetracyclic key intermediate of lumateperone

New approaches have been tested for the synthesis of lumateperone intermediates. As a result of these efforts, a novel synthesis of the late-stage tetracyclic key intermediate of lumateperone starting from the commercially available quinoxaline is described. The tetracyclic skeleton was constructed...

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Detalles Bibliográficos
Autores principales: Milen, Mátyás, Nyulasi, Bálint, Nagy, Tamás, Simig, Gyula, Volk, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194496/
https://www.ncbi.nlm.nih.gov/pubmed/35800146
http://dx.doi.org/10.3762/bjoc.18.66