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Assessment of Mitochondrial Function and Oxygen Consumption Measured During Ex Vivo Normothermic Machine Perfusion of Injured Pig Kidneys Helps to Monitor Organ Viability

Donor kidney assessment may improve organ utilisation. Normothermic Machine Perfusion (NMP) has the potential to facilitate this advance. The mechanism of action is not yet determined and we aimed to assess mitochondrial function during NMP. Anaesthetised pigs (n = 6) had one kidney clamped for 60 m...

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Detalles Bibliográficos
Autores principales: Hunter, James P., Faro, Letizia Lo, Rozenberg, Kaithlyn, Dengu, Fungai, Ogbemudia, Anne, Weissenbacher, Annemarie, Mulvey, John F., Knijff, Laura, Gopalakrishnan, Kishore, Ploeg, Rutger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194576/
https://www.ncbi.nlm.nih.gov/pubmed/35711321
http://dx.doi.org/10.3389/ti.2022.10420