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Physiological Roles of Monomeric Amyloid-β and Implications for Alzheimer’s Disease Therapeutics

Alzheimer’s disease (AD) progressively inflicts impairment of synaptic functions with notable deposition of amyloid-β (Aβ) as senile plaques within the extracellular space of the brain. Accordingly, therapeutic directions for AD have focused on clearing Aβ plaques or preventing amyloidogenesis based...

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Detalles Bibliográficos
Autores principales: Jeong, Hyomin, Shin, Heewon, Hong, Seungpyo, Kim, YoungSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194638/
https://www.ncbi.nlm.nih.gov/pubmed/35673997
http://dx.doi.org/10.5607/en22004