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Novel switchable ECF sigma factor transcription system for improving thaxtomin A production in Streptomyces
The application of the valuable natural product thaxtomin A, a potent bioherbicide from the potato scab pathogenic Streptomyces strains, has been greatly hindered by the low yields from its native producers. Here, we developed an orthogonal transcription system, leveraging extra-cytoplasmic function...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194655/ https://www.ncbi.nlm.nih.gov/pubmed/35756964 http://dx.doi.org/10.1016/j.synbio.2022.05.010 |