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Novel switchable ECF sigma factor transcription system for improving thaxtomin A production in Streptomyces

The application of the valuable natural product thaxtomin A, a potent bioherbicide from the potato scab pathogenic Streptomyces strains, has been greatly hindered by the low yields from its native producers. Here, we developed an orthogonal transcription system, leveraging extra-cytoplasmic function...

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Detalles Bibliográficos
Autores principales: Zhao, Xuejin, Wei, Weijia, Zong, Yeqing, Bai, Chaoxian, Guo, Xian, Zhu, Hua, Lou, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194655/
https://www.ncbi.nlm.nih.gov/pubmed/35756964
http://dx.doi.org/10.1016/j.synbio.2022.05.010