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Modelling the structure of Short Gastrulation and generation of a toolkit for studying its function in Drosophila

A BMP gradient is essential for patterning the dorsal-ventral axis of invertebrate and vertebrate embryos. The extracellular BMP binding protein Short Gastrulation (Sog) in Drosophila plays a key role in BMP gradient formation. In this study, we combine genome editing, structural and developmental a...

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Detalles Bibliográficos
Autores principales: Frampton, Sophie L., Sutcliffe, Catherine, Baldock, Clair, Ashe, Hilary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194680/
https://www.ncbi.nlm.nih.gov/pubmed/35603711
http://dx.doi.org/10.1242/bio.059199