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Modelling the structure of Short Gastrulation and generation of a toolkit for studying its function in Drosophila
A BMP gradient is essential for patterning the dorsal-ventral axis of invertebrate and vertebrate embryos. The extracellular BMP binding protein Short Gastrulation (Sog) in Drosophila plays a key role in BMP gradient formation. In this study, we combine genome editing, structural and developmental a...
Autores principales: | Frampton, Sophie L., Sutcliffe, Catherine, Baldock, Clair, Ashe, Hilary L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194680/ https://www.ncbi.nlm.nih.gov/pubmed/35603711 http://dx.doi.org/10.1242/bio.059199 |
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