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Leptin favors Th17/Treg cell subsets imbalance associated with allergic asthma severity

BACKGROUND: Obesity has often been associated with severe allergic asthma (AA). Here, we analyzed the frequency of different circulating CD4(+)T‐cell subsets from lean, overweight and obese AA patients. METHODS: Mononuclear cells from peripheral blood were obtained from 60 AA patients and the freque...

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Detalles Bibliográficos
Autores principales: Vollmer, Carolina M., Dias, Aleida S. O., Lopes, Lana M., Kasahara, Taissa M., Delphim, Letícia, Silva, Júlio Cesar C., Lourenço, Lucas Paulo, Gonçalves, Hilary Cesário, Linhares, Ulisses C., Gupta, Sudhir, Bento, Cleonice A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194742/
https://www.ncbi.nlm.nih.gov/pubmed/35734271
http://dx.doi.org/10.1002/clt2.12153