Stable Isotope Tracing Uncovers Reduced γ/β-ATP Turnover and Metabolic Flux Through Mitochondrial-Linked Phosphotransfer Circuits in Aggressive Breast Cancer Cells

Changes in dynamics of ATP γ- and β-phosphoryl turnover and metabolic flux through phosphotransfer pathways in cancer cells are still unknown. Using (18)O phosphometabolite tagging technology, we have discovered phosphotransfer dynamics in three breast cancer cell lines: MCF7 (non-aggressive), MDA-M...

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Detalles Bibliográficos
Autores principales: Klepinin, Aleksandr, Miller, Sten, Reile, Indrek, Puurand, Marju, Rebane-Klemm, Egle, Klepinina, Ljudmila, Vija, Heiki, Zhang, Song, Terzic, Andre, Dzeja, Petras, Kaambre, Tuuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194814/
https://www.ncbi.nlm.nih.gov/pubmed/35712500
http://dx.doi.org/10.3389/fonc.2022.892195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194814/
https://www.ncbi.nlm.nih.gov/pubmed/35712500
http://dx.doi.org/10.3389/fonc.2022.892195

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